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Advanced / Aggressive Protocol (2 mL = ~10.0 mg/mL) Note: The 12 mg dose represents the highest dose tested in Phase 2 trials [3] [4] , producing maximum weight-loss efficacy (~24% body weight at 48 weeks)

NOTE: Dont crush or chew the metformin prolonged release tabled because it can cause a released of whole active drug immediatley which can increase risk of side effect and also therapeutic efficacy and duration of action is decreased

New Medications : Such as Luspatercept, which is designed to improve hemoglobin levels

The FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed

[DOI] [PubMed] [Google Scholar] 61.He L., Feng D., Guo H., Zhou Y., Li Z., Zhang K., Zhang W., Wang S., Wang Z., Hao Q., et al